Manindra Bera

This paper introduces DNA nanorings to dynamically control membrane tension in sub-100 nm liposomes, enabling controlled mechanical stress and molecular cargo release.

This study shows that two Munc13 oligomers are essential for vesicle docking and SNARE assembly, supporting neurotransmitter release.

The paper identifies a minimal set of presynaptic proteins that regulate different modes of Ca2+-triggered vesicle fusion and short-term plasticity.

This paper identifies Synaptophysin as a chaperone that organizes 12 SNAREpins under each synaptic vesicle through its hexamer structure and VAMP2 dimer binding.

The paper reconstitutes core synaptic machinery to reveal DAG's role in vesicle priming and Ca2+-triggered release, showing DAG accelerates SNAREpin assembly and affects release dynamics.

This study investigates the independent yet synergistic roles of Synaptotagmin-1 and Complexin in calcium-regulated neuronal exocytosis using a reconstituted single-vesicle fusion assay.