Jie Zhu

The paper uses untargeted metabolomic profiling to show that mTORC1 regulates amino acid utilization in lymphatic endothelial cells, affecting glutaminolysis and branched-chain amino acid metabolism.

This study investigates the role of PFKFB2 in cardiac metabolic flexibility and glucose utilization, finding that its loss impairs mitochondrial function and affects systemic glucose homeostasis under stress.

The paper investigates the role of the PXDLS/T-binding cleft in Ribeye's function at synaptic ribbons, showing that mutations in this region impair ribbon structure and synaptic transmission in zebrafish.

The paper combines mathematical modeling and experiments to show Synaptotagmin rings act as Ca2+-sensitive fusion clamps and docking sensors in synaptic vesicle release.