Author

Pierre R. Dubus

Université de BordeauxORCID 0000-0003-1803-4711Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Assay:proteomics· 1

Frequent Co-Authors

Armelle MénardiD· 1 shared Brianna Rodgers· 1 shared Christine VaroniD· 1 shared David BernardiD· 1 shared David VindrieuxiD· 1 shared Delphine Goehrig· 1 shared Elodie SifréiD· 1 shared Fumihito MiuraiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Armelle MénardORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 3, 2026

Cytolethal distending toxin promotes epithelial-to-mesenchymal transition by modulating AKT-Dependent β-catenin Ser552 phosphorylation

Ruxue Jia, Lamia Azzi Martin, Mariana Saraiva…·Armelle Ménard

This study shows that CDT induces β-catenin Ser552 phosphorylation via AKT, leading to EMT and cancer-related changes in epithelial cells.

DOI 10.64898/2026.06.01.729203

humanproteomics

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Molecular BiologyNature CommunicationsPeer-reviewedJul 1, 2025

DNA methylation protects cancer cells against senescence

Xiaoying Chen, Kosuke Yamaguchi, Brianna Rodgers…·Pierre‐Antoine Defossez

The paper shows that reduced DNA methylation in cancer cells leads to senescence without DNA damage, involving p21 and cGAS, and demonstrates this in vivo.

17 citationstop 1%

humanDNA methylation

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