Tongchao Li

A Multimodal Adaptive Optical Microscope For In Vivo Imaging from Molecules to Organisms

The paper introduces MOSAIC, a multimodal adaptive optical microscope that enables non-invasive imaging across biological scales in live specimens.

Dimensionality reduction simplifies synaptic partner matching in an olfactory circuit

The paper shows that dimensionality reduction simplifies synaptic partner matching in the fly antennal lobe by reducing a 3D search problem to a 1D trajectory.

Molecular and Cellular Mechanisms of Teneurin Signaling in Synaptic Partner Matching

This study identifies the intracellular signaling pathway of teneurins in synaptic partner matching using Drosophila models.

Origin of wiring specificity in an olfactory map: dendrite targeting of projection neurons

This study investigates how projection neurons in Drosophila establish wiring specificity in the olfactory map through lineage, birth order, and dynamic dendrite remodeling during development.

Transcription Factor Acj6 Controls Dendrite Targeting via CombinatorialCell-Surface Codes

This study identifies Acj6 as a transcription factor that controls dendrite targeting in Drosophila PNs by regulating combinatorial expression of cell-surface proteins.

Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila

The paper generates single-cell transcriptomes of Drosophila olfactory receptor neurons across development and adulthood, revealing stable receptor expression and cell-type-specific transcriptomic features.

Temporal evolution of single-cell transcriptomes of Drosophila olfactory projection neurons

The paper analyzes single-cell transcriptomes of Drosophila olfactory projection neurons across developmental stages to identify transcriptomic changes and cellular diversity patterns.

Cellular Bases of Olfactory Circuit Assembly Revealed by Systematic Time-lapse Imaging

The paper uses time-lapse imaging in Drosophila to study how olfactory receptor neurons target axons to specific glomeruli, revealing dynamics of branching and bilateral interactions.

Cell-Surface Proteomic Profiling in the Fly Brain Uncovers New Wiring Regulators

The paper profiles cell-surface proteomes in Drosophila olfactory neurons across development, identifying new regulators of neural circuit assembly.

Coordinating Receptor Expression and Wiring Specificity in Olfactory Receptor Neurons

The paper identifies transcription factors that coordinate olfactory receptor expression and wiring specificity in Drosophila ORNs using single-cell RNA-sequencing and genetic analysis.

Classifying Drosophila Olfactory Projection Neuron Subtypes by Single-cell RNA Sequencing

This study uses single-cell RNA sequencing to classify Drosophila olfactory projection neuron subtypes and identifies key transcription factors and molecular codes involved in their specification.