Jaroslav Oľha

This study compares fragment-based and dissociation-based protocols for culturing glioblastoma organoids, finding that fragment-based methods better preserve tumor biology and extracellular matrix features.

AlphaFind v2 enables fast, structure-based search across protein structures and domains, using embeddings and US-align for refinement and supporting organism and CATH-based filtering.

This study shows HSV-1 infection induces Aβ clustering and neurodegeneration pathways in iPSC-derived neurons, supporting the pathogen infection hypothesis for Alzheimer's disease.

AlphaFind provides a web-based tool for fast structure-based retrieval of protein structures from AlphaFold DB using 3D features and machine learning.