Author

Bryan Serrels

Edinburgh Cancer ResearchORCID 0000-0003-1826-4584Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adam ByroniD· 1 shared Alison F. MunroiD· 1 shared Andrew D. CampbelliD· 1 shared Andrew Victor BiankiniD· 1 shared Billie G. C. GriffithiD· 1 shared Catriona A. FordiD· 1 shared Colin NixoniD· 1 shared Courtney BulliD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Adam ByronORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer ResearchPeer-reviewedDec 5, 2024

A targetable PREX2/RAC1/PI3Kβ signalling axis confers resistance to clinically relevant therapeutic approaches in melanoma

Catriona A. Ford, Dana Koludrović, Patricia P. Centeno…·Andrew D. Campbell

This study identifies a druggable PREX2/RAC1/PI3Kβ signalling axis in BRAF-mutant melanoma that confers resistance to therapies and can be targeted to improve treatment outcomes.

8 citations

mousehuman

𝕏 PostBluesky

GenomicsScientific ReportsPeer-reviewedJan 8, 2021

FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs

Billie G. C. Griffith, Rosanna Upstill‐Goddard, Holly Brunton…·Margaret C. Frame

This study shows FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs through ATAC-seq and RNA-seq integration.

22 citations

humanATAC-seq

𝕏 PostBluesky