BiochemistrybioRxivPreprint
Structural basis for a phosphoinositide-driven mTORC2-AKT positive feedback loop
Iain M. Hay, Maxime Bourguet, Bilal Ahsan…·Roger L. Williams
This study reveals the structural basis of a phosphoinositide-driven mTORC2-AKT positive feedback loop through cryo-EM structures and functional analysis.
DOI 10.64898/2026.01.08.698367