Author

Thomas Gassler

Austrian Centre of Industrial Biotechnology (Austria)ORCID 0000-0003-1873-8807Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:yeast· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Diethard MattanovichiD· 2 shared Brigitte GasseriD· 1 shared Charles Moritz· 1 shared David Glinsner· 1 shared Lisa LutziD· 1 shared Matthias G. SteigeriD· 1 shared Michael BaumschabliD· 1 shared Michael SaueriD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Diethard MattanovichORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryMetabolic EngineeringPeer-reviewedAug 25, 2026

Alcohol dehydrogenase-mediated methanol dissimilation increases carbon efficiency in synthetic autotrophic yeast

Charles Moritz, Lisa Lutz, Michael Baumschabl…·Özge Ata

This study improves carbon efficiency in autotrophic yeast by redirecting methanol dissimilation through alcohol dehydrogenase, increasing biomass yield and product titers.

DOI 10.1016/j.ymben.2026.102529

yeastmetabolomics

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintDec 3, 2019

A synthetic Calvin cycle enables autotrophic growth in yeast

Thomas Gassler, Michael Sauer, Brigitte Gasser…·Matthias G. Steiger

This paper demonstrates that metabolic engineering can convert the yeast Pichia pastoris from heterotrophic to autotrophic growth by rewiring its carbon assimilation pathway to resemble the Calvin-Benson-Bassham cycle.

3 citations

yeastexperimental assay

𝕏 PostBluesky