Wayne S. Sossin

The paper investigates ribosome clusters in neuronal RNA granules, finding they contain stalled ribosomes and unique 3D structures that avoid quality-control mechanisms.

The paper investigates the role of FMRP in neuronal RNA granules containing stalled ribosomes and finds that its loss affects granule stability but not ribosome stalling sites.

The paper shows that puromycylated peptides remain in neuronal ribosomes in a hybrid state, revealing a distinct conformation and stalling mechanism in neurons.

The paper identifies mRNA sequences that stall ribosomes in neurons, linking these sequences to FMRP association and stalled polysome function.

The paper demonstrates a method to measure synaptic strength at individual contacts in Aplysia sensory-motor neuron synapses over multiple days using calcium transients.

The paper uses MRI and beta-galactosidase expression to study Capn15 knockout mice, revealing brain size reductions and expression patterns in adult mice.

The paper shows that isoform-specific stabilization of PKMs by KIBRA determines isoform specificity during long-term facilitation in Aplysia.