Author

Dhiraj Acharya

Cleveland ClinicORCID 0000-0003-1929-3870Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Michaela Ulrike GackiD· 2 shared Abel Viejo‐BorbollaiD· 1 shared Adalbert KrawczykiD· 1 shared Alberto CataneseiD· 1 shared Alicia GorethiD· 1 shared Angela RosenbohmiD· 1 shared Anna Ponomarenko· 1 shared Anne FinkiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Michaela Ulrike GackORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 27, 2026

Herpes simplex virus infection promotes ALS pathology through ICP0-mediated PML body disruption

Dennis Freisem, Daniel Rombach, Sarah J. Brockmann…·Karin M. Danzer

This study shows HSV infection increases ALS risk and promotes TDP-43 pathology through ICP0-mediated disruption of PML bodies.

3 citations

humanstatistical model

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ImmunologyProceedings of the National Academy of SciencesPeer-reviewedApr 4, 2025

MDA5 ISGylation is crucial for immune signaling to control viral replication and pathogenesis

Lucky Sarkar, Guanqun Liu, Dhiraj Acharya…·Michaela U. Gack

This study shows that MDA5 ISGylation is essential for antiviral immunity, as its disruption leads to impaired cytokine responses and increased viral replication in mice.

21 citationstop 2%

mouseexperimental assay

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