Author
Harvard UniversityORCID 0000-0003-1946-8677Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
John Hintze, Asli B. Topaktas, Thomas Daugbjerg Madsen…·Katrine T.-B. G. Schjoldager
The paper shows that O-glycans in LRP1's ligand-binding domains differentially modulate uptake of tau and amyloid beta, but not RAP or ApoE.
Florian Georgescauld, Sonia Okekenwa, Tanner Boyd…·Yuyu Song
This study identifies dynamic conformational states of soluble Tau that precede aggregation and correlate with neuronal toxicity in Alzheimer's disease and related tauopathies.
Noé Quittot, Dhanush Sivasankaran, Dorothea Böken…·Bradley T. Hyman
The paper identifies rare bioactive tau oligomers in Alzheimer's brain that can induce templated misfolding and fibril formation, distinguishing them from non-bioactive oligomers.