Briana K. Chen

The paper develops and tests novel 5-HT4R-targeting compounds that reduce stress-induced maladaptive behaviors in mice, showing efficacy across age groups.

This study investigates the combined effects of (R,S)-ketamine and prucalopride on stress-induced behaviors and neural activity, finding additive benefits in reducing fear, despair, and hyponeophagia.

This study tests if 5-HT4R agonists can prevent stress-induced behaviors in mice, finding that some are effective as prophylactics.

This study shows that (R,S)-ketamine and (2R,6R)-hydroxynorketamine prevent stress-induced depressive-like behavior in female mice, with ovarian hormones mediating their efficacy.