Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewed
CYK-1/Formin activation in cortical RhoA signaling centers promotes organismal left-right symmetry breaking
Teije Corneel Middelkoop, Júlia Garcia-Baucells, Porfirio Quintero-Cadena…·Stephan W. Grill
The paper shows CYK-1/Formin activation in RhoA foci generates active torque in the actomyosin cortex, driving chiral counter-rotation and left-right symmetry breaking in C. elegans embryos.
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