Porfirio Quintero-Cadena

The paper introduces a high-throughput platform to generate large datasets for training machine learning models to predict antibody developability properties.

The paper shows CYK-1/Formin activation in RhoA foci generates active torque in the actomyosin cortex, driving chiral counter-rotation and left-right symmetry breaking in C. elegans embryos.

The paper investigates how CTD length and disorder affect transcriptional bursting using smFISH, live imaging, and RNA-seq, finding that length modulates burst size and frequency while disorder mediates CTD-CTD interactions essential for transcription.

This study identifies affl-2, a C. elegans ortholog of the human AF4/FMR2 family, as a regulator of heat shock induced gene expression.