NeurosciencebioRxivPreprint
Microglia Depletion Reduces Human Neuronal APOE4-Driven Pathologies in a Chimeric Alzheimer's Disease Model
Antara T. Rao, Nuo Chen, Min Joo Kim…·Yadong Huang
The paper investigates the role of microglia in APOE4-driven Alzheimer's pathology using a chimeric model, finding that microglia are required for APOE4-induced pathologies.