Shinji Takamatsu

This study shows hypoxia reduces LRIG1 protein levels in colorectal cancer organoids despite increased mRNA, suggesting limitations in LRIG1-based cancer therapies under hypoxic conditions.

This paper shows prohaptoglobin promotes pancreatic cancer by sustaining YAP activity, enabling cells to bypass contact inhibition and enhance motility and tumor growth.

The paper investigates the role of Enterococcus faecalis in the progression of latent chronic pancreatitis associated with pancreatic cancer tissue through pathological and serological analyses.

This study identifies LRP1 as a core-fucosylated protein regulated by FUT8 in liver cancer, showing its role in cell proliferation and signaling.

The paper investigates how glycosylation and splicing variants of LRIG1 affect EGFR proteostasis in cancer, finding that N74Q mutation and exon 2 skipping enhance LRIG1-EGFR binding and degradation.