Author

Jodie S. Chandler

Malaghan Institute of Medical ResearchORCID 0000-0003-2003-573XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:genome assembly· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Abbie R. LarsoniD· 1 shared Andrew J. YatesiD· 1 shared Arpit Chandan SwainiD· 1 shared Benedict P. SeddoniD· 1 shared Bernard HenrissatiD· 1 shared Caterina CarcoiD· 1 shared Cayman WilliamsiD· 1 shared Christiaan Hendrik van DorpiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

Abbie R. LarsonORCID

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3 papers

Recent·Most cited

IL-2- and IL-4-dependent signaling play separate and sequential roles in the differentiation of GATA3-hi TH2 cells in vivo

Greta R. Webb, Caterina Carco, Shaiu-Choot Tang, Marie Sophie Fabre, Sotaro Ochiai, Abbie R. Larson, Jodie S. Chandler, Kerry L. Hilligan, Evelyn J. Hyde, Samuel I. Old, Olivier Lamiable, Franca Ronchese

This study shows IL-2 is needed for GATA3 upregulation in TH2 cells, while IL-4 promotes their proliferation and effector function in vivo.

bioRxiv · Mar 5, 2026 · PreprintImmunology

Tissue resident memory CD4+ T cells are sustained by site-specific levels of self-renewal and continuous replacement

Jodie S. Chandler, M. Elise Bullock, Arpit Chandan Swain, Cayman Williams, Christiaan Hendrik van Dorp, Benedict P. Seddon, Andrew J. Yates

The paper quantifies self-renewal and replacement rates of CD4+ TRM in skin and gut LP using fate mapping and models, finding site-specific differences in residency and turnover.

eLife · Jun 25, 2025Peer-reviewedImmunology

De novo long-read assembly of a complex animal genome

David Eccles, Jodie S. Chandler, Mali Camberis, Bernard Henrissat, Sergey Koren, Graham S Le Gros, Jonathan J. Ewbank

The paper demonstrates de novo long-read genome assembly of Nippostrongylus brasiliensis using MinION data, revealing complex DNA repeats and haplotypic variants.

BMC Biology · Jan 11, 2018Peer-reviewedGenomics