Author

Heinz Steffens

Universitätsmedizin GöttingenORCID 0000-0003-2005-325XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Assay:imaging· 3 Research Focus:cell type annotation· 2 Research Focus:spatial domain detection· 2 Research Focus:cell-cell communication· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Carola GregoriD· 2 shared Fred WolfiD· 2 shared Kamila A. KiszkaiD· 2 shared Katrin I. WilligiD· 2 shared Waja Wegner· 2 shared Alexander Charles MottiD· 1 shared Christian DulliniD· 1 shared Ellen Rothermel· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioengineering

Carola GregorORCID

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Author profile →

4 papers

Recent·Most cited

Autonomous bioluminescence emission from transgenic mice

Kamila A. Kiszka, Christian Dullin, Heinz Steffens, Tanja Koenen, Ellen Rothermel, Frauke Alves, Carola Gregor

This paper generates a transgenic mouse line that autonomously emits bioluminescence in vivo without requiring exogenous substrates.

Science Advances · Jul 9, 2025Peer-reviewedBioengineering

MINFLUX fluorescence nanoscopy in biological tissue

Thea Moosmayer, Kamila A. Kiszka, Volker Westphal, Jasmin K. Pape, Marcel Leutenegger, Heinz Steffens, Seth G. N. Grant, Steffen J. Sahl, Stefan W. Hell

This study demonstrates MINFLUX fluorescence nanoscopy's ability to achieve sub-10 nm resolution for protein localization in thick mouse brain tissue sections.

Proceedings of the National Academy of Sciences · Dec 20, 2024Peer-reviewedBiophysics

Environmental enrichment enhances patterning and remodeling of synaptic nanoarchitecture revealed by STED nanoscopy

Waja Wegner, Heinz Steffens, Carola Gregor, Fred Wolf, Katrin I. Willig

The paper uses STED nanoscopy to show environmental enrichment sharpens synaptic nanoarchitecture dynamics and enhances synaptic precision.

eLife · Feb 23, 2022Peer-reviewedNeuroscience

Stable but not rigid: Long-term in vivo STED nanoscopy uncovers extensive remodeling of stable spines and indicates multiple drivers of structural plasticity

Heinz Steffens, Alexander Charles Mott, Siyuan Li, Waja Wegner, Pavel Švehla, Vanessa W. Y. Kan, Fred Wolf, Sabine Liebscher, Katrin I. Willig

This study uses in vivo STED nanoscopy to show that dendritic spines undergo extensive remodeling over time, with both volatile and stable components, and this is exaggerated in a neurodegeneration model.

Science Advances · Jun 9, 2021Peer-reviewedNeuroscience