Sabine Liebscher

This study investigates how anti-NMDAR encephalitis alters neuronal network function by enhancing coupling and clustering in hippocampal neurons during slow-wave sleep.

This study shows that NMDAR autoantibodies disrupt the excitatory-inhibitory balance in the hippocampus, leading to network hypersynchrony and symptoms resembling schizophrenia.

This study uses in vivo STED nanoscopy to show that dendritic spines undergo extensive remodeling over time, with both volatile and stable components, and this is exaggerated in a neurodegeneration model.

This study shows that cytoplasmic FUS mislocalization in mice causes behavioral changes and inhibitory synaptic defects without widespread neuronal loss.

This study shows that injecting alpha-synuclein fibrils into the striatum of mice leads to altered cortical neuron function and reduced inhibitory cells in the somatosensory cortex.

The paper investigates long-term neuronal activity dynamics in Alzheimer’s disease using calcium imaging in transgenic mice, finding stable aberrant activity patterns and a progressive gain of activity in certain neurons.

This study shows that cortical circuit alterations, including increased neuronal activity and reduced inhibitory synapses, occur before disease onset in Huntington’s disease mice.