Author

Yuping Li

University of California, San FranciscoORCID 0000-0003-2057-3271Unclaimed ORCID profile · follow to get notified of new preprints

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Yuping Li1 paper · University of California, San Francisco

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Adair L. BorgesiD· 1 shared Alan AshworthiD· 1 shared Daphne CheniD· 1 shared Dmitri A. PetroviD· 1 shared Dominique H. SmithiD· 1 shared G. J. CorreyiD· 1 shared Gavin SherlockiD· 1 shared Grant KinsleriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

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10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Adair L. BorgesORCID

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2 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedAug 14, 2025

AcrIF11 is a potent CRISPR-specific ADP-ribosyltransferase encoded by phage and plasmid

Daphne Chen, Leah T. Roe, Yuping Li…·James S. Fraser

This study characterizes AcrIF11, an ADP-ribosyltransferase that inhibits CRISPR-Cas systems with high potency and specificity, and shows its reversibility through macrodomain enzymes.

4 citations

bacteria (other)proteomics

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Evolutionary BiologybioRxivPreprintApr 17, 2024

A shift from pleiotropic to modular adaptation revealed by a high-resolution two-step adaptive walk

Grant Kinsler, Yuping Li, Gavin Sherlock, Dmitri A. Petrov

This study shows that early adaptive mutations in yeast are pleiotropic, while later mutations are modular, focusing on respiration over fermentation.

DOI 10.1101/2024.04.17.589938

yeastwhole-genome sequencing

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