Multi-nucleation in two-cell human embryos stems from spindle and metaphase plate incoherence in the first mitosis
Gerard H. Pieper, Mansour Aboelenain, Lucy Munro…·Adèle L. Marston
The paper investigates the causes of multi-nucleation in two-cell human embryos and finds that spindle and metaphase plate incoherence during the first mitosis leads to this phenomenon.