Author
MRC Centre for Regenerative MedicineORCID 0000-0003-2071-1590Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Peter Donlon, Paula Sotelo‐Parrilla, David MacKenzie MacLeod…·Dónal O’Carroll
The paper determines the structure of the apo-PIWIL4-HSP90 complex and shows it adopts an open conformation distinct from piRNA-bound PIWI.
Anna Fleming, Elena V. Knatko, Xiang Li…·Kasper Dindler Rasmussen
This study shows PROSER1 regulates DNA demethylation through dual mechanisms, balancing gene expression and preventing developmental malformations.
Nicholas Vrettos, Jan Oppelt, Ansgar Zoch…·Zissimos Mourelatos
This study shows that MIWI arginines are essential for spermatogenesis by regulating transposons, piRNA amplification, and spermiogenic transcript stabilization.