Monika E. Dolega

This study shows mechanical compression remodels the nucleolus, reduces rDNA transcription, and identifies nucleolin as a mediator of this response through biophysical and epigenetic mechanisms.

The paper shows that wound healing in Drosophila involves reversible chromatin-lamina dewetting triggered by mechanical changes, leading to cellular contraction and tissue repair.

The paper investigates how mechanical stress is dissipated in folded epithelia, revealing that calcium waves and nuclear tension changes coordinate this process.