Pierre Cordelier

This study identifies the entry mechanisms of SG33, an oncolytic myxoma virus, into pancreatic cancer cells, showing it uses macropinocytosis and clathrin-mediated endocytosis.

The paper identifies TGN46 as a host factor critical for H-1PV infection in pancreatic cancer cells through a CRISPR-Cas9 screen and functional analyses.

This study uses a microfluidic model to show that senescent fibroblasts cause ECM softening through collagen network reorganization without changing permeability.

This study shows TRIP12's intrinsically disordered region drives chromatin condensate formation, disrupting DNA damage response and genome accessibility.