David Anthony Mahns

This study identifies fast-conducting mechano-nociceptors as essential for mechanical nocifensive behaviors and sensitization in mice and humans.

This study investigates the effect of blocking Aβ fibers on pain perception and nociceptive withdrawal reflexes in humans, finding that Aβ fibers may contribute to pain and reflex signaling.

The paper identifies PIEZO2-dependent mechanical pain in humans and mice, showing hair-pull pain is mediated by Aβ inputs and specific nociceptors.

The paper investigates short-latency nociceptive withdrawal reflex responses in humans and finds they are as painful as conventional latency responses, suggesting they may be mediated by ultrafast nociceptors.

The paper investigates pain hypersensitivity in humans during acute muscle pain, finding that sub-perceptual stimulation of adjacent, contralateral, and remote muscles increases pain by 12-17%.

The paper shows that spiking patterns, not receptor type, determine vibrotactile frequency perception, suggesting a universal frequency decoding system.