Felipe Meira de‐Faria

Central role for fast nociceptors in mechanical nocifensive behavior and sensitization

This study identifies fast-conducting mechano-nociceptors as essential for mechanical nocifensive behaviors and sensitization in mice and humans.

Hierarchical organization of mechano-nociceptive pathways revealed by activity labeling

The paper maps nociceptive signaling architecture by combining activity labeling with single-cell RNA sequencing, revealing a hierarchical organization of mechano-nociceptor populations based on tissue domain and organ context.

Genetic targeting of myelinated primary afferent neurons using a new NefhCreERT2 knock-in mouse

This paper introduces a new NefhCreERT2 knock-in mouse line for selectively targeting myelinated primary afferent neurons, enabling genetic studies of these fibers while excluding unmyelinated C fibers.

A fast nociceptive subsystem mediating rapid reflexive behavior but not affective pain

The paper identifies a fast nociceptive pathway that mediates rapid reflexive behavior but not affective pain.

PIEZO2-dependent rapid pain system in humans and mice.

The paper identifies PIEZO2-dependent mechanical pain in humans and mice, showing hair-pull pain is mediated by Aβ inputs and specific nociceptors.