Kim I. Chisholm

High-throughput light-sheet 3D microscopy of whole rodent brain microstructure for integration with MRI

The paper integrates 3D light-sheet microscopy with diffusion MRI to predict cellular features from MRI data across multiple mouse strains.

Characterising the stimulus-response function of mouse C-low threshold mechanoreceptors to mechanical stimuli in vivo

This study uses in vivo calcium imaging to characterize the stimulus-response function of mouse C-low threshold mechanoreceptors to mechanical stimuli.

In vivo calcium imaging shows that satellite glial cells have increased activity in painful states

This study uses in vivo calcium imaging to show that satellite glial cells show increased activity in painful states, with some signals linked to neuronal firing and others occurring independently.

Assessing spontaneous sensory neuron activity using in vivo calcium imaging

This paper assesses spontaneous sensory neuron activity using in vivo calcium imaging and develops a machine learning algorithm to predict spontaneous activity with high accuracy across different pain models and labs.

The impact of bone cancer on the peripheral encoding of mechanical pressure stimuli

This study investigates how bone cancer affects the peripheral encoding of mechanical pressure stimuli by comparing sensory afferent responses in healthy and cancer-induced bone pain rats.

Large scale in vivo recording of sensory neuron activity with GCaMP6

This paper demonstrates a technique to monitor large-scale sensory neuron activity in vivo using GCaMP6, revealing polymodality and sensitization in nociceptors under inflammatory conditions.