Ulrike Topf

This study shows that zinc supplementation in aged C. elegans improves healthspan and protects against proteotoxicity by preserving translational proteostasis.

The paper investigates Rpl40 paralogs in yeast, showing they differentially affect mitochondrial proteome and lipid homeostasis under stress.

This study identifies a non-canonical role for prefoldin subunit 5 in proteasome assembly, showing its necessity for Rpt ring subcomplex formation and proteasome activity.

The paper analyzes protein thiol oxidation in aged yeast and creates a database for cross-species comparison of redoxome data.