BioengineeringACS Synthetic BiologyPeer-reviewed
Gut delivery of pentameric GLP-1 using genetically engineered Bacillus subtilis
Ningyuan Ye, Francesco Di Pierro, Nicola Zerbinati…·Jiahe Li
This paper develops an engineered Bacillus subtilis spore system for sustained gastrointestinal delivery of pentameric GLP-1, showing glucose-lowering and weight-reduction effects in mice.
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