Cyclin O controls entry into the cell-cycle variant required for multiciliated cell differentiation
Michella Khoury Damaa, Jacques Serizay, Rémi Balagué, Amélie-Rose Boudjema, Marion Faucourt, Nathalie Delgehyr, Kim Jee Goh, Hao Kim Lu, Ee Kim Tan, Cameron T. James, Catherine Faucon, Rana Mitri, Diana Carolin Bracht, Colin D. Bingle, Norris Ray Dunn, , Alice Meunier
Cyclin O is necessary for multiciliated cells to enter their differentiation cell cycle variant and allows the massive amplification of centrioles, which serve as basal bodies for cilia nucleation.
Cell Reports · Dec 30, 2024Peer-reviewedCell Biology