Yefeng Zheng

The paper introduces RiboCouple, a method that links RNA backbone geometry to sequence design using learned interaction topologies, improving refolding validity in RNA structure prediction.

siProGenA generates siRNA candidates by proposing positions and generating guide sequences, achieving high Hit@1 and Hit@5 scores in controlled evaluations.

Complete morphologies of 1,708 neurons, sparsely labelled and imaged whole-brain with fMOST, expose region-specific long-range projection rules and finer diversity than current transcriptomic subtypes capture.