Jonathan B. Demb

This study shows that Netrin-1 overexpression restores blood-retina barrier integrity in retinal diseases by reinforcing barrier stability through the Netrin-1/Unc5b signaling pathway.

This study examines how optic nerve injury affects the electrophysiological properties of a resilient retinal ganglion cell type, finding reduced firing and intrinsic excitability due to voltage-gated channel dysfunction and Ca2+-dependent mechanisms.

This study shows that early exposure to a Western diet in female mice leads to severe retinal and neurovascular issues, including anophthalmia and cataracts, highlighting the need for early intervention.

This study identifies and characterizes wide-field amacrine cells in mouse retina that encode stimulus orientation through molecular and functional analysis.

The paper identifies a novel interneuron type in the mouse retina that provides synaptic inhibition to the AII amacrine cell, crucial for night vision.

This study presents a circuit-inspired model explaining retinal ganglion cell firing precision and contrast adaptation through divisive suppression mechanisms.