Author

Karen Yu

Columbia UniversityORCID 0009-0002-3734-5478Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Assay:imaging· 1 Approach:mechanistic / dynamical model· 1 Assay:metabolomics· 1

Frequent Co-Authors

Alexander J. Devanny· 2 shared Laura J. KaufmaniD· 2 shared Anil K. RustgiiD· 1 shared Asja GuzmaniD· 1 shared Carol L. PrivesiD· 1 shared Gizem EfeiD· 1 shared Iris G. MerceriD· 1 shared Kausik RegunathiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

Alexander J. Devanny

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2 papers

Recent·Most cited

BiophysicsPRX LifePeer-reviewedJun 11, 2026

Nuclear Packing Sets Fluidity Along the Epithelial to Mesenchymal Spectrum

Karen Yu, Alexander J. Devanny, Laura J. Kaufman

The paper investigates how nuclear packing affects fluidity during epithelial-to-mesenchymal transition by analyzing spheroid coalescence and nuclear properties.

DOI 10.1103/1thq-kysn

imagingexperimental assay

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Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedOct 21, 2025

Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling.

Asja Guzman, Tatsuya Kawase, Alexander J. Devanny…·Carol L. Prives

This study shows mutant p53 promotes cancer cell invasion in 3D environments via mevalonate pathway-dependent Rho/ROCK signaling and ECM reorganization.

5 citations

humanproteomics

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