Author

Mags Gwynne

University of YorkORCID 0000-0003-2338-6965Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Dimitris LagosiD· 2 shared Anca M. FarcasiD· 1 shared Anob M. ChakrabartiiD· 1 shared Charlotte CapitanchikiD· 1 shared D. Marc JonesiD· 1 shared Dawn CoverleyiD· 1 shared Ioannis KourtzelisiD· 1 shared Iseabail FarquhariD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

Dimitris LagosORCID

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3 papers

Recent·Most cited

ImmunologyThe Journal of ImmunologyPeer-reviewedAug 28, 2025

Malat1 regulates female Th2 cell cytokine expression through controlling early differentiation and response to IL2

Mags Gwynne, Katie A. West, Stijn van Dongen…·Dimitris Lagos

This study shows Malat1 regulates cytokine expression in female Th2 cells by affecting early differentiation and IL2 response, but not in male cells.

3 citations

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintMar 6, 2025

PRMT activity promotes global 3' UTR shortening in proliferating cells

Llywelyn Griffith, Charlotte Capitanchik, Shaun Moore…·Jernej Ule

This study shows PRMT activity regulates 3' UTR shortening in proliferating cells through alternative polyadenylation, impacting cancer and immune-related diseases.

DOI 10.1101/2025.03.06.641848

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintOct 29, 2024

A co-transcriptional mechanism for tightly controlling RNA homeostasis in yeast

Sofia Esteban Serna, Tove Widén, Mags Gwynne…·Sander Granneman

The paper shows that the NNS complex regulates RNA homeostasis in yeast by controlling the expression of the mitochondrial transporter Pic2, with defects causing growth defects and stress.

DOI 10.1101/2024.10.29.620883

yeastexperimental assay

𝕏 PostBluesky