Characterization of a Novel Cell Wall-Associated Nucleotidase of Enterococcus faecalis that Degrades Extracellular c-di-AMP
Adriana G Morales Rivera, Anju Bala, Leila G. Casella, Debra N. Brunson, Ellsa Wongso, Aria Patel, Ilka E. Cuvilly, Alejandro Riveros Walker, Shannon M. Wallet, Ana Lidia Flores‐Mireles, Jose Abelardo C. Lemos
This paper characterizes EecP, a novel cell wall-anchored phosphodiesterase in E. faecalis that degrades extracellular c-di-AMP, showing its role in modulating host immune responses and infection outcomes.
PLoS Pathogens · May 20, 2026Peer-reviewedMicrobiology