NeuroscienceJournal of NeurochemistryPeer-reviewed
Antiretroviral treatment reveals a novel role for lysosomes in oligodendrocyte maturation
Lindsay K. Festa, Abigail E. Clyde, Caela C. Long…·Kelly L. Jordan‐Sciutto
This study shows that bictegravir inhibits oligodendrocyte maturation by causing lysosomal de-acidification, which can be reversed by activating TRPML1.
10 citations