Gabriela Salinas

This study examines natural cardiovascular aging in non-human primates, finding histological and molecular changes associated with aging, including fibrosis, inflammation, and atherosclerosis.

This study shows SMAD4 loss causes cancer chromosomal instability by inducing replication stress through transcription-replication conflicts via BMP signaling.

This study investigates the cooperative role of Emx2 and Dmrta2 in cortex development and reveals distinct functions of Dmrta2 in choroid plexus formation.

The paper shows that Dach1's temporal refinement is essential for the transcriptional maturation of somatosensory neurons.

This study identifies PRDM16-DT as an astrocyte-specific lncRNA downregulated in Alzheimer's disease, showing its role in maintaining astrocyte function and neuronal support.

The paper develops a single-nucleus full-length RNA-sequencing approach to identify intronic variants linked to mis-splicing in pancreatic cancer.

This study introduces a novel single-cell RNA-sequencing platform and applies it to analyze genotype-phenotype relationships in ageing disorders.

This paper shows that methotrexate inhibits SARS-CoV-2 replication in cell cultures and synergizes with remdesivir, suggesting potential for repurposing MTX in treating COVID-19.

This study shows that DNMT1 deletion in interneurons reduces age-related loss of cortical interneurons and improves somatomotor performance in mice.