Andrew N. Clarkson

This paper develops a thermoresponsive hydrogel loaded with BDNF to promote functional recovery after stroke in mice by modulating the post-stroke microenvironment.

This study investigates the function of a conserved genomic region linked to AIS by deleting it in mice, finding vertebral rotation and proprioceptive deficits similar to human AIS.

The paper identifies proteolytic events in neurons during excitotoxicity using N-terminomics, revealing calpain-mediated cleavage of synaptic proteins and potential therapeutic targets for neuroprotection.

This paper shows that the gliopeptide ODN, when administered after day 3 post-stroke, improves motor recovery in mice by correcting cortical excitability.