Author

Lihsia Chen

University of MinnesotaORCID 0000-0003-2386-7734Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 3 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Melinda Moseley-Alldredge· 2 shared Anthony R. BrauniD· 1 shared Calvin O’Keefe· 1 shared Caroline AragóniD· 1 shared Divya Alley· 1 shared Elly E. LiaoiD· 1 shared Hayoung Yoo· 1 shared Janet E. RichmondiD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersGenetics

Melinda Moseley-Alldredge

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 11, 2024

Fluorescence lifetime-based FRET biosensors for monitoring N-terminal domain interactions of TDP-43 in living cells: A novel resource for ALS and FTD drug discovery

Noah Nathan Kochen, Marguerite Murray, Nagamani Vunnam…·Jonathan N. Sachs

The paper develops FRET biosensors to monitor TDP-43 N-terminal domain interactions and identifies ketoconazole as a potential drug candidate for ALS and FTD.

4 citations

humanC. elegans

𝕏 PostBluesky

GeneticsbioRxivPreprintSep 14, 2024

The L1CAM SAX-7 is an antagonistic modulator of Erk signaling

Melinda Moseley-Alldredge, Caroline Aragón, Marcus Vargus…·Lihsia Chen

The paper shows SAX-7/L1CAM antagonizes ERK signaling in both neuronal and non-neuronal processes in C. elegans.

DOI 10.1101/2024.09.14.613091

C. elegansexperimental assay

𝕏 PostBluesky

GeneticsGeneticsPeer-reviewedNov 25, 2021

A role for the Erk MAPK pathway in modulating SAX-7/L1CAM-dependent locomotion in Caenorhabditis elegans

Melinda Moseley-Alldredge, Seema Sheoran, Hayoung Yoo…·Lihsia Chen

This study identifies a role for the Erk MAPK pathway in modulating SAX-7/L1CAM-dependent locomotion in C. elegans by analyzing genetic interactions and synaptic function.

8 citations

C. elegansexperimental assay

𝕏 PostBluesky