Janet E. Richmond

This study investigates how SNT-1 and SNT-3 mediate fast and slow neurotransmitter release in C. elegans by analyzing their interactions with SNARE complexes and polybasic motifs.

The paper identifies PHAC-1 as a regulator of synaptic transmission in C. elegans and shows that DEE70 variants disrupt cholinergic signalling at the neuromuscular junction.

The paper shows that UNC-8, an ENaC protein, promotes Ca2+-dependent endocytosis to dismantle and recycle presynaptic components during neuronal remodeling in C. elegans.

This study identifies a role for the Erk MAPK pathway in modulating SAX-7/L1CAM-dependent locomotion in C. elegans by analyzing genetic interactions and synaptic function.

The paper identifies a transcriptional pathway regulated by IRX-1 that drives the removal of presynaptic proteins during neuronal remodeling in C. elegans.

This study identifies UNC-10/RIM and SYD-2/Liprin-α as regulators of UNC-2 CaV2 channel clustering at presynaptic active zones in C. elegans, revealing redundant yet distinct mechanisms for active zone assembly.

This study shows ethanol exposure in C. elegans causes mitochondrial fragmentation and activates a stress response that counteracts muscle weakness.

This study identifies cla-1 as a novel C. elegans active zone gene, showing that specific isoforms regulate synapse development, synaptic vesicle clustering, and release.