Author

Nagamani Vunnam

University of MinnesotaORCID 0000-0003-3915-1159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1

Frequent Co-Authors

Anthony R. BrauniD· 2 shared Elly E. LiaoiD· 2 shared Jonathan N. SachsiD· 2 shared Noah Nathan KocheniD· 2 shared Aimee Renaud· 1 shared James R. DuttoniD· 1 shared Lihsia CheniD· 1 shared Marguerite MurrayiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Anthony R. BraunORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJun 4, 2026

From anti-fungal to potential neurotherapeutic: Posaconazole as an effective inhibitor of cellular TDP-43 pathology

Noah Nathan Kochen, Sophia Zafari, Aimee Renaud…·Jonathan N. Sachs

This study identifies posaconazole as a more effective and safer alternative to ketoconazole for inhibiting TDP-43 pathology in ALS/FTD by reducing aggregation and restoring SREBP2 levels.

DOI 10.64898/2026.06.01.728552

humanproteomics

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NeurosciencebioRxivPreprintOct 11, 2024

Fluorescence lifetime-based FRET biosensors for monitoring N-terminal domain interactions of TDP-43 in living cells: A novel resource for ALS and FTD drug discovery

Noah Nathan Kochen, Marguerite Murray, Nagamani Vunnam…·Jonathan N. Sachs

The paper develops FRET biosensors to monitor TDP-43 N-terminal domain interactions and identifies ketoconazole as a potential drug candidate for ALS and FTD.

4 citations

humanC. elegans

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