Author
Kim S. McKim
Rutgers, The State University of New JerseyORCID 0000-0002-8990-1168Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2019-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 31 mutual co-author links9 papers
Recent·Most cited
- GeneticsbioRxivPreprint
Exploring the C(2)M Cohesin Complex: Structure, Dynamics, and Ability to Facilitate Assembly of the Synaptonemal Complex
Margaret Howland, Helen Hieu Nguyen, Daria Mitri…·Kim S. McKim
This paper investigates the role of C(2)M in Drosophila meiosis, showing its interaction with SMC1 and SMC3 and its role in synaptonemal complex assembly.
- GeneticsPLoS GeneticsPeer-reviewed
Distinct checkpoint and homolog biorientation pathways regulate meiosis I in Drosophila oocytes
Joanatta G. Shapiro, Neha Changela, Janet Ko Jang…·Kim S. McKim
This study investigates SAC function and biorientation pathways in Drosophila meiosis I, finding SAC is not required for chromosome segregation but some SAC proteins are involved in biorientation.
2 citations - GeneticsMolecular Biology of the CellPeer-reviewed
Meiosis-specific functions of kinetochore protein SPC105R required for chromosome segregation in Drosophila oocytes
Jay N. Joshi, Neha Changela, Lia Mahal…·Kim S. McKim
This study identifies specific domains of SPC105R critical for meiosis I chromosome segregation in Drosophila oocytes by analyzing its functional regions and interactions.
5 citations - GeneticsPLoS GeneticsPeer-reviewed
A Dynamic population of prophase CENP-C is required for meiotic chromosome segregation
Jessica E. Fellmeth, Janet Ko Jang, Manisha Persaud…·Kim S. McKim
This study shows that CENP-C must be expressed during meiotic prophase to ensure proper chromosome segregation, unlike CID which remains stable without prophase expression.
14 citations - GeneticsbioRxivPreprint
Whole Transcriptome and Functional Analyses Identify Novel Genes Involved in Meiosis and Fertility in Drosophila melanogaster
Siqi Sun, Tyler Defosse, Ayla Boyd…·Kim S. McKim
The paper identifies 65 novel meiotic and fertility genes in Drosophila melanogaster through RNAi screening, showing their role in infertility and chromosomal nondisjunction.
DOI 10.1101/2023.05.12.540472 - GeneticsThe Journal of Cell BiologyPeer-reviewed
Oocyte spindle assembly depends on multiple interactions between HP1 and the CPC
Lin-Ing Wang, Tyler Defosse, Janet Ko Jang…·Kim S. McKim
The paper investigates the role of HP1 and CPC interactions in Drosophila oocyte spindle assembly and identifies their involvement in kinetochore formation and chromosome bi-orientation.
20 citations - GeneticsbioRxivPreprint
Multiple pools of Protein Phosphatase 2A-B56 function to antagonize spindle assembly, promote kinetochore attachments and maintain cohesion in Drosophila Oocytes
Janet K. Jang, Amy C. Gladstein, Arunika Das…·Kim S. McKim
The paper identifies the role of PP2A-B56 subunit in Drosophila oocytes, showing its necessity for sister chromatid cohesion, microtubule attachment, and metaphase I arrest during meiosis.
DOI 10.1101/2020.08.01.232512 - GeneticsPLoS GeneticsPeer-reviewed
Cohesin and microtubule dependent mechanisms regulate sister centromere fusion during meiosis I
Lin-Ing Wang, Arunika Das, Kim S. McKim
The paper identifies two mechanisms regulating sister centromere fusion during meiosis I in Drosophila oocytes: one involving SPC105R protecting cohesins and another involving PP1-87B regulating microtubule dynamics.
21 citations