Author

Tyler Defosse

Rutgers, The State University of New Jersey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 3

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Janet Ko JangiD· 3 shared Kim S. McKimiD· 3 shared Lin-Ing WangiD· 2 shared Neha Changela· 2 shared Arunika DasiD· 1 shared Ayla Boyd· 1 shared Diya Surray· 1 shared Faith Verderose· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenetics

Janet Ko JangORCID

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3 papers

Recent·Most cited

Meiosis-specific functions of kinetochore protein SPC105R required for chromosome segregation in Drosophila oocytes

Jay N. Joshi, Neha Changela, Lia Mahal, Janet Ko Jang, Tyler Defosse, Lin-Ing Wang, Arunika Das, Joanatta G. Shapiro, Kim S. McKim

This study identifies specific domains of SPC105R critical for meiosis I chromosome segregation in Drosophila oocytes by analyzing its functional regions and interactions.

Molecular Biology of the Cell · Jun 12, 2024Peer-reviewedGenetics

Whole Transcriptome and Functional Analyses Identify Novel Genes Involved in Meiosis and Fertility in Drosophila melanogaster

Siqi Sun, Tyler Defosse, Ayla Boyd, Joel Sop, Faith Verderose, Diya Surray, Mark Aziz, Margaret Howland, Siwen Wu, Neha Changela, Janet Ko Jang, Karen Schindler, Jinchuan Xing, Kim S. McKim

The paper identifies 65 novel meiotic and fertility genes in Drosophila melanogaster through RNAi screening, showing their role in infertility and chromosomal nondisjunction.

bioRxiv · May 12, 2023 · PreprintGenetics

Oocyte spindle assembly depends on multiple interactions between HP1 and the CPC

Lin-Ing Wang, Tyler Defosse, Janet Ko Jang, Rachel A. Battaglia, Victoria F. Wagner, Kim S. McKim

The paper investigates the role of HP1 and CPC interactions in Drosophila oocyte spindle assembly and identifies their involvement in kinetochore formation and chromosome bi-orientation.

The Journal of Cell Biology · Mar 12, 2021Peer-reviewedGenetics