Rachel A. Kocik

This study investigates how Pde2 regulates the yeast Environmental Stress Response by affecting Msn2/4 activation and target gene expression, with minimal impact on Dot6 repression.

This study shows that stress-defense factors in yeast regulate the repression of growth-promoting genes, coordinating resource reallocation needed for stress response.

The paper models single-cell phenotypes in yeast to show that transcriptional repression during stress improves post-stress growth recovery.

The paper identifies a genetic interaction between the Hda1C histone deacetylase and the H2B ubiquitylation pathway in regulating chromatin structure during transcription elongation in yeast.