The paper examines the spatial organization of dendritic cell subsets in NSCLC patients treated with anti-PD1 and finds that cDC1-driven patterns correlate with prolonged ICB response.

bioRxiv · May 7, 2026 · PreprintCancer Biology

IntegrAlign: A comprehensive tool for multiimmunofluorescence panel integration through image alignment

Léo Hermet, Léo Laoubi, Martial Scavino, Anne‐Claire Doffin, Alexia Gazeu, Justine Berthet, Berenice Pillat, Stéphanie Tissot-Renaud, Sylvie Rusakiewicz, Marie‐Cécile Michallet, Nathalie Bendriss‐Vermare, Jenny Valladeau‐Guilemond, Jean Hausser, Christophe Caux, Margaux Hubert

IntegrAlign integrates multiimmunofluorescence panels through image alignment, achieving sub-cellular precision and improving spatial analysis of tumor microenvironments.

Bioinformatics · Oct 15, 2025Peer-reviewedBioinformatics

Loss of TLR9 expression in breast cancer tumour cells and its role in the cell cycle.

Emily Sible, Gregory E. Weitsman, Salomé Amouyal, Guillaume Roblot, Marie Marotel, Rémi Pescarmona, Nathalie Bendriss‐Vermare, Cheryl Gillett, Amie Ceesay, Alexia Gazeu, Marie‐Cécile Michallet, Christophe Caux, François‐Loïc Cosset, Umaima Al‐Alem, Tony Ng, Uzma Ayesha Hasan

The paper shows reduced TLR9 expression in breast cancer cells and links it to decreased proliferation and activation of senescence-related factors.

Journal of Innate Immunity · Jun 23, 2025Peer-reviewedCell Biology