Author

Ian A. Simpson

Pennsylvania State UniversityORCID 0000-0003-2447-7877Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Avraham S. Lukacher· 1 shared Ethan S. LippmanniD· 1 shared Hyosung KimiD· 1 shared James R. ConnoriD· 1 shared Kondaiah PalsaiD· 1 shared Stephanie L. BaringeriD· 1 shared Vladimir S. SpiegelmaniD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Avraham S. Lukacher

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1 paper

Recent·Most cited

NeuroscienceJournal of NeurochemistryPeer-reviewedSep 4, 2023

Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin

Stephanie L. Baringer, Avraham S. Lukacher, Kondaiah Palsa…·James R. Connor

This study shows that amyloid-β exposure in astrocytes increases apo-transferrin levels, which enhances iron transport from endothelial cells at the blood-brain barrier, contributing to early iron accumulation in Alzheimer's disease.

20 citations

humanbulk RNA-seq

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