NeuroscienceJournal of NeurochemistryPeer-reviewed
Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin
Stephanie L. Baringer, Avraham S. Lukacher, Kondaiah Palsa…·James R. Connor
This study shows that amyloid-β exposure in astrocytes increases apo-transferrin levels, which enhances iron transport from endothelial cells at the blood-brain barrier, contributing to early iron accumulation in Alzheimer's disease.
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