James R. Connor

This study shows that iron deficiency in glioblastoma tumors affects immune interactions differently in males and females.

This study shows that tumor-associated macrophages protect glioblastoma cells from ferroptosis by releasing ferritin-bound iron via exosomes, reducing available iron for lipid peroxidation.

This study shows that brain inflammation increases iron accumulation in brain tissue via extracellular vesicles (EVs) released from blood-brain barrier endothelial cells, and inhibiting EVs reduces iron accumulation.

This study shows that amyloid-β exposure in astrocytes increases apo-transferrin levels, which enhances iron transport from endothelial cells at the blood-brain barrier, contributing to early iron accumulation in Alzheimer's disease.

The paper investigates the role of PAFR in ALS and suggests PAFR inhibitors as potential therapeutic agents, particularly for SOD1 familial ALS.