Aniella Bak

This paper benchmarks three graph construction methods for MEA recordings of human brain slices, showing method choice significantly affects network topology with effect sizes comparable to biological signals.

This study compares intrinsic and synaptic properties of human cortical neurons recorded on-site and off-site after a 30-40 minute transport, finding altered membrane potential, synaptic efficacy, and dendritic spine density.

This study analyzes human dendritic spine morphology and density using a unique dataset and deep learning, revealing sex and tissue-specific differences and changes over time in culture.

This study tracks neocortical development in organotypic mouse brain slice cultures over five weeks, revealing stable network properties by two weeks and increased variability later, with implications for disease research.

This paper provides a detailed protocol for long-term human organotypic brain slice cultures, enabling extended electrophysiological studies and viral transduction.

This study identifies and characterizes giant depolarizing potentials (GDPs) in human neocortical neurons, showing their modulation by norepinephrine and acetylcholine.