Enrica Bordignon

The paper demonstrates functional dynamics in the eukaryotic RNA exosome using NMR and EPR, showing subunit flexibility and conformational changes in the Exo9 complex.

The paper investigates how structural differences in Bcl2 proteins affect BH3 domain interactions and apoptotic function using simulations and experimental validation.

This study provides the structural model of the Bcl-xL/tBid complex at the mitochondrial membrane, revealing its dynamic architecture and mechanism of indirect apoptosis inhibition.

This study characterizes how full-length recombinant Bcl-xL monomers inhibit apoptosis through direct and indirect mechanisms using in vitro and organelle assays.

This study combines molecular dynamics simulations and EPR spectroscopy to measure rotational diffusion changes in γD-crystallin during liquid-liquid phase separation.

This study investigates the multi-state kinetics of Tc toxin prepore-to-pore transition, identifying intermediate states and transition times under various conditions.